Endocrine Abstracts

Background: Nowadays, primary hyperparathyroidism is usually diagnosed incidentally, in asymptomatic patients, while only around 15% of patients present the classical manifestations. Osteoclastoma, a benign bone lesion, is usually the late manifestation of hyperparathyroidism.Objective: We present the case of a 52 years old female (non-menopausal) recently diagnosed with ulnar osteoclastoma, primary hyperparathyroidism and secondary osteoporosis.<p c...

Introduction: Cushing disease is the most common cause of endogenous hypercortisolemia and most frequently is caused by microadenomas, but rarely, only in 10% to 20% of cases, the adenomas are large enough to produce mass effect.1Case report: We present the case of a 63 years old female patient, diagnosed in 2007 with a 22/18 mm non-secreting pituitary adenoma and panhypopituitarism. She undergone transsphenoidal surgery twice, followed by gam...

Background: Using new technologies, such as glucose sensors and insulin pumps, may help patients with type 1 diabetes mellitus achieve better glycemic control and quality of life. With the occasion of implementing the National Program for free distribution of continuous glucose monitoring systems (CGMS) starting with January 2019, children aged under 13 years were investigated in order to assess the association between previous use of CGMS and insulin pumps and the metabolic c...

Background: Type 1 diabetes is a chronic disease requiring constant management and a disciplined lifestyle, especially in children. Real-time continuous glucose monitoring system (RT-CGMS) can be a useful tool in maintaining good glycemic control. In our medical centre, beginning with January 2019, a National Program for free distribution of RT-CGMS has been set in motion. The results from one of our previous studies indicated a significant increase in glycosylated haemoglobin...

Introduction: Hybrid closed loop (HCL) systems are made up of continuous glucose monitoring (CGM) sensor, an algorithm that receives the readings from the CGM and an insulin pump able to deliver variable insulin doses according to the information received from the other two parts. Predictive low-glucose suspend (PLGS) insulin pump is able to stop the administration of insulin before hypoglycemia occurs. These new technologies are meant to improve the quality of life and help t...

Background: Real-Time Continuous Glucose Monitoring Systems (RT-CGMS) represent a minimally invasive method for frequent glucose monitoring, allowing a better glycemic control for patients with type 1 diabetes. With the occasion of implementing the National Program for free access to RT-CGMS, we assessed the 6 months impact of RT-CGMS on the metabolic control, evaluated by glycated haemoglobin (HbA1c).Methods: In this unicentric, prospective cohort study...

Introduction: Glucagonoma is a rare pancreatic neuroendocrine functional tumor, with an estimated incidence of 1 in 20 million people. At the moment of diagnosis, the majority of patients present locoregional and liver metastases.Case report: We present the case of a 46 years old male patient, diagnosed with glucagon secreting pancreatic neuroendocrine tumor in February 2018. As part of the glucagonoma syndrome, the patient was also suffering from insuli...

Objectives: In the last decades, thyroid cancer incidence has increased all over the world. This may be due to heightened medical surveillance and more addressability to surgery, as many cancers are diagnosed while under 1 cm. The aim of our study was to obtain data about the prevalence and histological subtypes of primary thyroid carcinoma in patients undergoing thyroidectomy.Materials and methods: We retrospectively analysed the files of 953 patients w...